Pediatric Bone Marrow Transplantation

In Acıbadem Health Group, there are 2 centers that provide special services to adult and pediatric patients in need of bone marrow transplantation due to some blood diseases or cancer types that may be seen at any age and accepted as a significant disease group due to the lethal consequences.

  • Acıbadem Atakent University Hospital - Pediatric Bone Marrow Transplantation Center
  • Acıbadem Adana Hospital - Pediatric Bone Marrow Transplantation Center

    Bone Marrow Centers supported with the Acıbadem infrastructure possess all the infrastructure and equipment necessary for transplantation. All services in the center are provided in international conditions and sterile settings. The inpatient unit enables the transplantation to be performed, and the outpatient clinic provides post transplant care services.

    What is a stem cell?

    Stem cells are the main cells that form all the tissues and organs in the body. Undifferentiated yet, they have the ability of dividing, self renewal, and transformation into organ and tissues.

    Blood is the liquid tissue of the body and produced in the bone marrow. Cells defined as hematopoietic or “blood producing stem cells” are located here. These are produced by the main cells in the bone marrow and released into the bloodstream when they reach the required maturity. Their numbers are constant, however they can reproduce themselves when necessary, they can also new and mature blood cells.

    How is stem cell transplantation performed?

    A place for new cells needs to be opened in the body of the patient who will undergo transplantation. The bone marrow of the patient will be destroyed by drugs and radiation prior to the operation.. This preparatory phase lasts an average of 7-8 days, and on the day it ends bone marrow transplantation is performed by giving new stem cells to the patient.

    Because the transplanted stem cells know where they will go and are programmed for these spots, they select and lodge in the locations of the bone marrow that are empty and ready to reproduce. Then they reproduce like a seed when they are provided with adequate nutritional conditions.

    What are the disease groups in which stem cells transplantation is performed?

    Blood Disorders

    Blood disorders constitute the largest group. Leukemias are the most common in this group.

    Among the leukemias that do not respond to treatment oR recur, bone marrow transplantation carries significance in the treatment of :

    * ALL (Acute Lymphoblastic Leukemia)
    * AML (Acute Myeloblastic Leukemia)
    * KML (Chronica Myeloblastic Leukemia)

    Bone marrow transplantation is considered as the first treatment option in some types of ALL.

    Bone marrow transplantation emerges as the only treatment method in aplastic anemia where the bone marrow cannot produce any cells. This disease may be present from birth or occur later. Some viruses, chemical substances, and drugs may result in aplastic anemia.

    Blood diseases existing from birth are also significant in bone marrow transplantation. Bone marrow transplantation is also applied as the sole treatment in thalessemia which also known as Mediterranean anemia, sickle cell anemia, and some rarely seen blood disorders.


    After blood diseases cancer is the second most common type of disease that requires bone marrow transplantation. Bone marrow transplantation is the only alternative in patients who do not respond to treatment or have a recurrunce, especially related to Non-Hodgkin’s lymphoma. In the cases of recurrence in Hodgkin’s lymphoma, which is another type of lymph node cancer, the same treatment is used. 

    All the text that is featured in contains general information.
    Friday, August 17, 2018 2:22:27 AM